Upcoming Events

July 19-23, 2013: 21st Annual International Conference on Intelligent Systems for Molecular Biology (ISMB).

April 7-10, 2013: 17th Annual International Conference on Research in Computational Molecular Biology (RECOMB).

April 15-19, 2013: IEEE Symposium on Computational Intelligence in Bioinformatics & Computational Biology.

March 4-6, 2013: 5th international conference on Bioinformatics & Computational Biology (BICoB).

More events....


Oct 18, 2012: A new Postdoctoral Fellow, Dr. Sitanshu Sekhar Sahu has joined our lab.

Aug 13-17, 2012: A comprehensive 1-week Bioinformatics Workshop was organized on campus; co-organized by OSU's iCREST center. Visit facebook page for details.

Apr 23, 2012: Co-hosted Dr. James Tiedje (Director, NSF Center for Microbial Ecology, Michigan State University) as an invited iCREST speaker; see flyer for details.

Apr 13, 2012: World renowned Computational Biologist, Dr. Eugene Koonin (NCBI) visited our lab, and delivered an invited lecture on campus as part of iCREST speaker series; see flyer for details. Video on YouTube.

Mar 16, 2012: We welcome Dr. Chris Town (Group leader, Plant Genomics, JCVI) as an invited iCREST speaker; see flyer for details.

Feb 14, 2012: KBL receives new grant from OCAST to develop bioinformatics systems for plant-microbe interaction networks; immediate Postdoc opening available.

Oct 21, 2011: We welcome Dr. Patrick X. Zhao (Head, Bioinformatics Lab, Noble Foundation) as an invited iCREST speaker; see flyer for details.

Sep 17, 2011: Tyler Weirick joins our lab (under iCREST) as a Graduate Research Assistant.

Aug 17, 2011: Robyn Kelley, a new master's student joins our lab as a Graduate Research Assistant.

July 21, 2011: KBL receives OSU funding to establish an iCREST center for Bioinformatics and Computational Biology.

June 08, 2011: KBL welcomes its first student, Kalpana Varala to work as a summer scholar in lab.


Welcome to the NIMFFAB Bioinformatics Laboratory

Following recent advances in technology and the development of ultra high-throughput research, the field of biotechnology is beginning to suffer from data overload, and thus, applications of Bioinformatics & Computational Biology have expanded with these so-called '-omics' technologies (Genomics, Transcriptomics, Proteomics, Metabolomics). This discipline now sits as an umbrella over biotechnology. NIMFFAB is engaged in analyzing such large-scale sequence data, developing novel computational tools / algorithms and incorporating them into bioinformatics resources / databases. NIMFFAB is located on the first floor of OSU's new establishment, the Henry Bellmon Research Center.

National Institute for Microbial Forensics & Food and Agricultural Biosecurity (NIMFFAB) is, a coalition of National and State investigators conducting research on crop and food biosecurity and forensics issues. NIMFFAB assess current National capabilities for microbial forensics as related to plant pathogens and food safety and provides strategic planning, a long-range vision and prioritization of needs and resources related to plant and food-related microbial forensics and agricultural biosecurity.

Our bioinformatics research interests span a range of topics in applying statistical pattern recognition, artificial intelligence and machine learning technologies in the area of agricultural biosecurity, metagenomics, regulatory mechanisms of gene expression, genome-wide host-pathogen interaction networks and genome annotation for functional studies. Through collaborations NIMFFAB developed bioinformatics tools that are useful within the real biological situations. These include algorithms for pathogen detection and discrimination, identification of species-specific signatures, and using artificial intelligence to predict biosecurity threats. For example, discriminating pathogen genotypes in a fundamentally different way from distance-based and BLAST algorithms and instead, using the Neural Networks, Support Vector Machine or Decision Tree classifiers to build patterns from genome regions (e.g. DNA barcodes) that are under selective pressure; and ultimately incorporating them into a database(s) / visualization tool(s).

Our lab has active collaborations with the Samuel Roberts Noble Foundation, located in Ardmore (OK), focusing on basic plant biology research aimed at software development in computational biology, bioinformatics and genomics for biological discovery.